Recombinant Human PSPH protein, His-tagged

• Cat.No.: PSPH-201H
• Product Overview: Recombinant Human PSPH fused with His tag at C-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.
• Form: 50mM Tris, 250mM NaCl, 50mM Imidazole, pH 8.5.
• Molecular Mass: 26.1 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PSPH phosphoserine phosphatase [ Homo sapiens ]
• Official Symbol: PSPH
• Synonyms: PSPH; phosphoserine phosphatase; PSP; PSPase; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase; PSPHD
• Gene ID: 5723
• mRNA Refseq: NM_004577
• Protein Refseq: NP_004568
• MIM: 172480
• UniProt ID: P78330
• Chromosome Location: 7p11.2
• Pathway: Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Serine biosynthesis, organism-specific biosystem
• Function: calcium ion binding; hydrolase activity; magnesium ion binding; phosphoserine phosphatase activity; phosphoserine phosphatase activity; protein homodimerization activity