Recombinant Human PSMD3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PSMD3-6294H
• Product Overview: PSMD3 MS Standard C13 and N15-labeled recombinant protein (NP_002800) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 61 kDa
• AA Sequence: MKQEGSARRRGADKAKPPPGGGEQEPPPPPAPQDVEMKEEAATGGGSTGEADGKTAAAAAEHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVQGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASNTLLPEVEAYLQLLVVIFMMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSVARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQADGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PSMD3 proteasome 26S subunit, non-ATPase 3 [ Homo sapiens (human) ]
• Official Symbol: PSMD3
• Synonyms: PSMD3; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; tissue specific transplantation antigen 2, TSTA2; 26S proteasome non-ATPase regulatory subunit 3; P58; Rpn3; S3; proteasome subunit p58; 26S proteasome regulatory subunit S3; 26S proteasome regulatory subunit RPN3; tissue specific transplantation antigen 2; RPN3; TSTA2
• Gene ID: 5709
• mRNA Refseq: NM_002809
• Protein Refseq: NP_002800
• MIM: 617676
• UniProt ID: O43242