Recombinant Human PRRG2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRRG2-591H
• Product Overview: PRRG2 MS Standard C13 and N15-labeled recombinant protein (NP_000942) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 22.2 kDa
• AA Sequence: MRGHPSLLLLYMALTTCLDTSPSEETDQEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTGGILLIVLAGLGAFWYLRWRQHRGQQPCPQEAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYTSLRRPHTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRRG2 proline rich and Gla domain 2 [ Homo sapiens (human) ]
• Official Symbol: PRRG2
• Synonyms: PRRG2; proline rich Gla (G-carboxyglutamic acid) 2; proline rich Gla (G carboxyglutamic acid) polypeptide 2; transmembrane gamma-carboxyglutamic acid protein 2; PRGP2; proline-rich Gla protein 2; proline-rich gamma-carboxyglutamic acid protein 2; proline-rich Gla (G-carboxglutamic acid) polypeptide 2; proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
• Gene ID: 5639
• mRNA Refseq: NM_000951
• Protein Refseq: NP_000942
• MIM: 604429
• UniProt ID: O14669