Recombinant Human Protein Kinase C, Eta, GST-tagged, Active

• Cat.No.: PRKCH-403H
• Product Overview: Recombinant human full-length PKCeta was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=103 kDa.

Specification

• Cat. No.: PRKCH-403H
• Description: PKCη is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKCη is predominantly expressed in squamous cell epithelia and induces terminal differentiation of keratinocytes. PKCη that is endogenously expressed or overexpressed is found to associate with the cyclin E/cdk2/p21 complex in keratinocytes of mice and humans.
• Source: Sf9 insect cells using baculovirus.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: PRKCH protein kinase C, eta [ Homo sapiens ]
• Synonyms: PRKCH; protein kinase C, eta; PKCL; PKC-L; PRKCL; MGC5363; MGC26269; nPKC-eta; Protein kinase C eta type; EC 2.7.11.13
• Gene ID: 5583
• mRNA Refseq: NM_006255
• Protein Refseq: NP_006246
• UniProt ID: P24723
• Chromosome Location: 14q23.1
• MIM: 605437
• Pathway: Tight junction; Vascular smooth muscle contraction
• Function: ATP binding; protein kinase C activity; enzyme binding; metal ion binding; nucleotide binding; transferase activity; zinc ion binding