Recombinant Human protein C receptor, endothelial Protein, His&Flag tagged

• Cat.No.: PROCR-097H
• Product Overview: Recombinant human EPCR/PROCR/CD201 protein (Q9UNN8) (Ser 18-Ser 210) with both His, Flag tag at the C-terminus was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: 18-210aa
• Description: The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
• Tag: C-His&Flag
• Molecular Mass: 24.7 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: PROCR protein C receptor, endothelial [ Homo sapiens (human) ]
• Official Symbol: PROCR
• Synonyms: PROCR; protein C receptor, endothelial; endothelial protein C receptor; CCD41; CD201; EPCR; APC receptor; centrocyclin; CD201 antigen; activated protein C receptor; endothelial cell protein C receptor; cell cycle, centrosome-associated protein; CCCA; bA42O4.2; MGC23024
• Gene ID: 10544
• mRNA Refseq: NM_006404
• Protein Refseq: NP_006395
• MIM: 600646
• UniProt ID: Q9UNN8