Recombinant Human PROC Protein, MYC/DDK-tagged

• Cat.No.: PROC-3000H
• Product Overview: Recombinant Human PROC protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 50 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PROC protein C (inactivator of coagulation factors Va and VIIIa) [ Homo sapiens ]
• Official Symbol: PROC
• Synonyms: APC; PC; PROC1; THPH3; THPH4
• Gene ID: 5624
• mRNA Refseq: NM_000312
• Protein Refseq: NP_000303
• MIM: 612283
• UniProt ID: P04070