Recombinant Human PRELP Protein, MYC/DDK-tagged

• Cat.No.: PRELP-2906H
• Product Overview: Recombinant Human PRELP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRELP proline/arginine-rich end leucine-rich repeat protein [ Homo sapiens ]
• Official Symbol: PRELP
• Synonyms: MST161; MSTP161; SLRR2A
• Gene ID: 5549
• mRNA Refseq: NM_002725
• Protein Refseq: NP_002716
• MIM: 601914
• UniProt ID: P51888