Recombinant Human PPT1, Fc-tagged

• Cat.No.: PPT1-366H
• Product Overview: A DNA sequence encoding the human PPT1 (P50897-1)(Met1-Gly306) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Protein Length: Met1-Gly306
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human PPT1/Fc comprises 520 amino acids and has a predicted molecular mass of 58.3 kDa. The apparent molecular mass of the protein is approximately 58-67 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >85 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: PPT1 palmitoyl-protein thioesterase 1 [ Homo sapiens ]
• Official Symbol: PPT1
• Synonyms: PPT1; palmitoyl-protein thioesterase 1; PPT; ceroid lipofuscinosis; neuronal 1; infantile; CLN1; INCL; PPT-1; palmitoyl-protein hydrolase 1; ceroid-palmitoyl-palmitoyl-protein thioesterase 1
• Gene ID: 5538
• mRNA Refseq: NM_000310
• Protein Refseq: NP_000301
• MIM: 600722
• UniProt ID: P50897
• Chromosome Location: 1p32
• Pathway: Fatty acid elongation, organism-specific biosystem; Fatty acid elongation, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: hydrolase activity; palmitoyl-(protein) hydrolase activity; palmitoyl-(protein) hydrolase activity; palmitoyl-(protein) hydrolase activity; palmitoyl-(protein) hydrolase activity; palmitoyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activity