Recombinant Human POLR2C, T7-tagged

• Cat.No.: POLR2C-3055H
• Product Overview: Recombinant Human POLR2C was produced inE.coliwith a T7 tag at N-terminus. MW = 31441 Da (1-275 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-275 a.a.
• Description: DNA-directed RNA polymerase II subunit RPB3 is an enzyme that in humans is encoded by the POLR2C gene. This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa [ Homo sapiens ]
• Synonyms: POLR2C; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; RPB3; RPB31; hRPB33; hsRPB3; DNA-directed RNA polymerase II subunit RPB3; RPB33; RNA polymerase II subunit 3; RNA polymerase II subunit B3; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II 33 kDa polypeptide; EC 2.7.7.6; polymerase (RNA) II (DNA directed) polypeptide C (33kD)
• Gene ID: 5432
• mRNA Refseq: NM_032940
• Protein Refseq: NP_116558
• MIM: 180663
• UniProt ID: P19387
• Chromosome Location: 16q13-q21
• Pathway: Huntington"s disease; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; RNA polymerase
• Function: DNA binding; DNA-directed RNA polymerase activity; protein dimerization activity; contributes_to protein kinase activity