Recombinant Human PLK4 (G95L) Protein, GST-tagged

• Cat.No.: PLK4-01H
• Product Overview: Recombinant human PLK4 (G95L) (1-836) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: 120 kDa
• Purity: > 90%
• Applications: Kinase Assay
• Stability: One year at -70 centigrade from date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05 μg/μL
• Storage Buffer: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT and 25% glycerol.
• Protein length: 1-836 a.a.

Gene Information

• Gene Name: PLK4 polo like kinase 4 [ Homo sapiens (human) ]
• Official Symbol: PLK4
• Synonyms: PLK4; polo like kinase 4; SAK; STK18; MCCRP2; serine/threonine-protein kinase PLK4; serine/threonine-protein kinase 18; serine/threonine-protein kinase Sak; EC 2.7.11.21
• Gene ID: 10733
• mRNA Refseq: NM_014264
• Protein Refseq: NP_055079
• MIM: 605031
• UniProt ID: O00444