Recombinant Human Pim-2 Oncogene, GST-His

• Cat.No.: PIM2-727H
• Product Overview: RecombinantHuman PIM2, Amino acids M1-P311, N-terminally fused to GST-HIS6-Thrombin cleavage site, was expressed inSf9cells. MW = 64,096 Da.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 1-311 a.a.
• Description: PIM2 is a scoring system for rating the severity of medical illness for children, one of several ICU scoring systems. Its name stands for "Paediatric Index of Mortality". It has been designed to provide a predicted mortality for a patient by following a well defined procedure. Predicted mortalities are good when dealing with several patients, because the average predicted mortality for a group of patients is an indicator for the morbidity of these patients.
• Purification: One-step affinity purification using GSH-agarose.
• Product Identity: PIM2 was confirmed as PIM2 by specific Western Blotting using anti PIM2 antibody.
• Storage Buffer: 50 mM Tris-HCl, pH 8.0; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol.
• Concentration: 0.216 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
• Specific Activity: 35 pmol/μg×min.
• Storage: -80°C. Avoid repeated freeze-thaw cycles!

Gene Information

• Gene Name: PIM2 pim-2 oncogene [ Homo sapiens ]
• Synonyms: PIM2; pim-2 oncogene; PIM; Proto-oncogene serine/threonine-protein kinase Pim-2; EC 2.7.11.1; Pim-2h
• Gene ID: 11040
• mRNA Refseq: NM_006875
• Protein Refseq: NP_006866
• MIM: 300295
• UniProt ID: Q9P1W9
• Chromosome Location: Xp11.23
• Pathway: Acute myeloid leukemia
• Function: ATP binding; nucleotide binding; transferase activity; protein serine/threonine kinase activity; metal ion binding