Recombinant Human PIK3C3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | PIK3C3-2394H |
Product Overview : | PIK3C3 MS Standard C13 and N15-labeled recombinant protein (NP_002638) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes. |
Molecular Mass : | 101.4 kDa |
AA Sequence : | MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRKTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name | PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 [ Homo sapiens (human) ] |
Official Symbol | PIK3C3 |
Synonyms | PIK3C3; phosphoinositide-3-kinase, class 3; phosphatidylinositol 3-kinase catalytic subunit type 3; Vps34; PI3K type 3; PI3-kinase type 3; PtdIns-3-kinase type 3; phosphatidylinositol 3-kinase p100 subunit; VPS34; hVps34; MGC61518; |
Gene ID | 5289 |
mRNA Refseq | NM_002647 |
Protein Refseq | NP_002638 |
MIM | 602609 |
UniProt ID | Q8NEB9 |
◆ Recombinant Proteins | ||
PIK3C3-144HFL | Active Recombinant Full Length Human PIK3C3 Protein, N-His-tagged | +Inquiry |
PIK3C3-6736M | Recombinant Mouse PIK3C3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3C3-1723H | Recombinant Human PIK3C3 protein, His-tagged | +Inquiry |
PIK3C3-166H | Active Recombinant Human PIK3C3 protein, GST-tagged | +Inquiry |
PIK3C3-4120R | Recombinant Rat PIK3C3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PIK3C3-3190HCL | Recombinant Human PIK3C3 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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