Recombinant Human PHLDA2, His-tagged

• Cat.No.: PHLDA2-2400H
• Product Overview: Recombinant human PHLDA2 protein, fused to His-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques, 19.2 kDa (172aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PHLDA2, also known as Pleckstrin homology-like domain family A member 2, is a cytoplasmic protein that is involved in fetal and placental growth. It is an apoptosis-related protein that acts as a negative growth regulator and is expressed during normal human development. This protein is imprinted on placenta, liver and fetal tissues during embryogenesis and is removed once development is complete.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT.
• Purity: > 80% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MKSPDEVLRE GELEKRSDSL FQLWKKKRGV LTSDRLSLFP ASPRARPKEL RFHSILKVDC VERTGKYVYF TIVTTDHKEI DFRCAGESCW NAAIALALID FQNRRALQDF RSRQERTAPA APAEDAVAAA AAAPSEPSEP SRPSPQPKPR TP.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PHLDA2 pleckstrin homology-like domain, family A, member 2 [ Homo sapiens ]
• Synonyms: pleckstrin homology-like domain, family A, member 2; IPL; BRW1C; BWR1C; HLDA2; TSSC3; PHLDA2; pleckstrin homology-like domain family A member 2; p17-BWR1C; tumor-supressing STF cDNA 3; p17-Beckwith-Wiedemann region 1C; p17-Beckwith-Wiedemann region 1 C; tumor-suppressing STF cDNA 3 protein; imprinted in placenta and liver protein; tumor suppressing subtransferable candidate 3; tumor suppressing subchromosomal transferable fragment cDNA 3; beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein; imprinted in placenta and liver; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein; Imprinted in placenta and liver protein; Tumor-suppressing STF cDNA 3 protein
• Gene ID: 7262
• mRNA Refseq: NM_003311
• Protein Refseq: NP_003302
• MIM: 602131
• UniProt ID: Q53GA4
• Chromosome Location: 11p15.5