Recombinant Human PDP2, His-tagged

• Cat.No.: PDP2-30496TH
• Product Overview: Recombinant full length Human PDP2 with His tag.

Specification

• Species: Human
• Tag: His
• Protein Length: 463 amino acids
• Description: PDH kinases (PDKs) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDKs are present in an organ-dependent manner.
• Conjugation: HIS
• Form: Liquid
• Storage buffer: pH: 7.50Constituents:0.14% Sodium phosphate, 1.46% Sodium chloride, 30% Glycerol, 0.08% DTT, 0.02% EDTA, 0.05% Triton-X-100
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the PP2C family.

Gene Information

• Gene Name: PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 [ Homo sapiens ]
• Official Symbol: PDP2
• Synonyms: PDP2; pyruvate dehyrogenase phosphatase catalytic subunit 2; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; KIAA1348; PPM2C2; protein phosphatase 2C; magnesium dependent; catalytic subunit 2
• Gene ID: 57546
• mRNA Refseq: NM_020786
• Protein Refseq: NP_065837
• Uniprot ID: Q9P2J9
• Chromosome Location: 16q22.1
• Pathway: Metabolism, organism-specific biosystem; Pyruvate metabolism, organism-specific biosystem; Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystem; Regulation of pyruvate dehydrogenase (PDH) complex, organism-specific biosystem; TCA Cycle, organism-specific biosystem
• Function: [pyruvate dehydrogenase (lipoamide)] phosphatase activity; hydrolase activity; magnesium-dependent protein serine/threonine phosphatase activity; metal ion binding