Recombinant Human PDE9A Protein, His-tagged

• Cat.No.: PDE9A-2568H
• Product Overview: Recombinant Human PDE9A Protein (Ile290-Arg549) with a N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.0 kDa
• Protein length: Ile290-Arg549
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration ≤0.1 mg/mL. Do not vortex.

Gene Information

• Gene Name: PDE9A phosphodiesterase 9A [ Homo sapiens (human) ]
• Official Symbol: PDE9A
• Synonyms: PDE9A; phosphodiesterase 9A; high affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A; phosphodiesterase PDE9A21; CGMP-specific 3,5-cyclic phosphodiesterase type 9; HSPDE9A2; FLJ90181
• Gene ID: 5152
• mRNA Refseq: NM_001001567
• Protein Refseq: NP_001001567
• MIM: 602973
• UniProt ID: O76083