Recombinant Human PCSK9 Protein, C-AVI tagged, Biotinylated
Cat.No. : | PCSK9-33H |
Product Overview : | Recombinant Human Proprotein Convertase 9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln692 is expressed with a AVI tag at the C-terminus. |
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Species : | Human |
Source : | Human Cells |
Tag : | Avi |
Protein Length : | Gln31-Gln692(Val474Ile, Gly670Glu) |
Description : | Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER, the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development. |
Endotoxin : | Less than 0.1 ng/μg (1 EU/μg) |
Storage Buffer : | Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, pH 7.4. |
Shipping : | Dry ice/Polar packs |
Gene Name | PCSK9 proprotein convertase subtilisin/kexin type 9 [ Homo sapiens (human) ] |
Official Symbol | PCSK9 |
Synonyms | Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9; NARC1 |
Gene ID | 255738 |
mRNA Refseq | NM_174936 |
Protein Refseq | NP_777596 |
MIM | 607786 |
UniProt ID | Q8NBP7 |
◆ Recombinant Proteins | ||
PCSK9-3811H | Recombinant Human PCSK9 Protein (Gln31-Gln152, Ser153-Gln692), C-His tagged | +Inquiry |
PCSK9-352H | Active Recombinant Human PCSK9 Protein, His & Avi-tagged, Biotinylated | +Inquiry |
PCSK9-187H | Active Recombinant Human PCSK9 protein, Avi-His-tagged, Biotinylated | +Inquiry |
Pcsk9-412M | Recombinant Mouse Pcsk9 Protein, His-tagged | +Inquiry |
PCSK9-3812H | Recombinant Human PCSK9 Protein (Gln31-Gln692), N-His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PCSK9-2306RCL | Recombinant Rat PCSK9 cell lysate | +Inquiry |
PCSK9-2564MCL | Recombinant Mouse PCSK9 cell lysate | +Inquiry |
PCSK9-2775RCL | Recombinant Rhesus PCSK9 cell lysate | +Inquiry |
PCSK9-2875HCL | Recombinant Human PCSK9 cell lysate | +Inquiry |
Not For Human Consumption!
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