Recombinant Human PASK Protein (S949-S1323), GST tagged

Description :	Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation.
Source :	Insect cell
Species :	Human
Tag :	GST
Form :	Liquid
Protein length :	S949-S1323
Endotoxin :	< 0.01 EU per μg of the protein
Purity :	90%
Stability :	Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Storage :	Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer :	Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Shipping :	It is shipped out with blue ice.

Gene Name	PASK PAS domain containing serine/threonine kinase [ Homo sapiens (human) ]
Official Symbol	PASK
Synonyms	PASK; PAS domain containing serine/threonine kinase; PAS domain-containing serine/threonine-protein kinase; KIAA0135; PASKIN; STK37; per-arnt-sim (PAS) domain kinase; DKFZp434O051; DKFZp686P2031;
Gene ID	23178
mRNA Refseq	NM_001252119
Protein Refseq	NP_001239048
MIM	607505
UniProt ID	Q96RG2