Recombinant Human Parvin, Alpha, His-tagged

Cat.No. : PARVA-7196H
Product Overview : Recombinant human PARVA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 44.6 kDa.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 1-372aa
Description : Alpha-parvin, also known as PARVA, probably plays a role in the regulation of cell adhesion and cytoskeleton organization. This protein plays a role in ciliogenesis.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
Molecular Mass : 44.6 kDa (395aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMATSPQK SPSVPKSPTP KSPPSRKKDD SFLGKLGGTL ARRKKAKEVS ELQEEGMNAI NLPLSPIPFE LDPEDTMLEE NEVRTMVDPN SRSDPKLQEL MKVLIDWIND VLVGERIIVK DLAEDLYDGQ VLQKLFEKLE SEKLNVAEVT QSEIAQKQKL QTVLEKINET LKLPPRSIKW NVDSVHAKSL VAILHLLVAL SQYFRAPIRL PDHVSIQVVV VQKREGILQS RQIQEEITGN TEALSGRHER DAFDTLFDHA PDKLNVVKKT LITFVNKHLN KLNLEVTELE TQFADGVYLV LLMGLLEGYF VPLHSFFLTP DSFEQKVLNV SFAFELMQDG GLEKPKPRPE DIVNCDLKST LRVLYNLFTK YRNVE
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name PARVA parvin, alpha [ Homo sapiens ]
Official Symbol PARVA
Synonyms PARVA; parvin, alpha; matrix remodelling associated 2 , MXRA2; alpha-parvin; FLJ10793; FLJ12254; actopaxin; matrix-remodeling-associated protein 2; calponin-like integrin-linked kinase-binding protein; MXRA2; CH-ILKBP; FLJ25106; FLJ46049;
Gene ID 55742
mRNA Refseq NM_018222
Protein Refseq NP_060692
MIM 608120
UniProt ID Q9NVD7
Chromosome Location 11p15.3
Pathway Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-extracellular matrix interactions, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Localization of the PINCH-ILK-PARVIN complex to focal adhesions, organism-specific biosystem; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components, organism-specific biosystem;
Function actin binding; protein binding;

Not For Human Consumption!

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