Recombinant Human PAOX Protein, MYC/DDK-tagged
| Cat.No. : | PAOX-251H |
| Product Overview : | Recombinant human PAOX protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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| Description : | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. [UniProtKB/Swiss-Prot Function] |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc&DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
| Molecular Mass : | 34.5 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name | polyamine oxidase [ Homo sapiens ] |
| Official Symbol | PAOX |
| Synonyms | PAO; PAO |
| Gene ID | 196743 |
| mRNA Refseq | NM_152911.2 |
| Protein Refseq | NP_690875.1 |
| UniProt ID | Q6QHF9 |
Not For Human Consumption!
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