Recombinant Human P2RY2 Protein, His-tagged

• Cat.No.: P2RY2-2540H
• Product Overview: Recombinant Human P2RY2 Protein (Gly310-Leu377) with a N-His tag was expressed in E. coli.

Specification

• Description: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 11.3 kDa
  Accurate Molecular Mass: 16 kDa
• Protein length: Gly310-Leu377
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: P2RY2 purinergic receptor P2Y, G-protein coupled, 2 [ Homo sapiens (human) ]
• Official Symbol: P2RY2
• Synonyms: P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R
• Gene ID: 5029
• mRNA Refseq: NM_176072
• Protein Refseq: NP_788086
• MIM: 600041
• UniProt ID: P41231