Recombinant Human OSTM1 Protein, MYC/DDK-tagged

• Cat.No.: OSTM1-450H
• Product Overview: Recombinant human OSTM1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 37.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: osteopetrosis associated transmembrane protein 1 [ Homo sapiens ]
• Official Symbol: OSTM1
• Synonyms: GIPN; GL; HSPC019; OPTB5
• Gene ID: 28962
• mRNA Refseq: NM_014028.3
• Protein Refseq: NP_054747.2
• MIM: 607649
• UniProt ID: Q86WC4