Recombinant Human OSMR&IL6ST protein, His-Flag-tagged

• Cat.No.: OSMR&IL6ST-1436H
• Product Overview: Recombinant Human OSMR&IL6ST protein(Q99650-1(OSMR)&P40189-1(IL6ST))(Glu28-Met740(OSMR) & Glu23-Glu619(IL6ST)), fused with C-terminal His and Flag tag, was expressed in HEK293.

Specification

• Species: Human
• Source: C-His-Flag
• ProteinLength: Glu28-Met740(OSMR) & Glu23-Glu619(IL6ST)
• Tag: C-His-Flag
• Form: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human OSMR&GP130, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 82.2 kDa(OSMR) and 68.83 kDa(GP130). Due to glycosylation, the protein migrates to 100-140 kDa based on Tris-Bis PAGE result.
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC.
• Storage: Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• Reconstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: OSMR oncostatin M receptor [ Homo sapiens ]
• Official Symbol: OSMR
• Synonyms: OSMR; oncostatin M receptor; oncostatin-M-specific receptor subunit beta; OSMRB; IL-31RB; IL-31R-beta; IL-31R subunit beta; IL-31 receptor subunit beta; interleukin-31 receptor subunit beta; oncostatin-M specific receptor beta subunit; PLCA1; MGC75127; MGC150626; MGC150627
• Gene ID: 9180
• mRNA Refseq: NM_001168355
• Protein Refseq: NP_001161827
• MIM: 601743
• UniProt ID: Q99650
• Gene Name 2: IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) [ Homo sapiens ]
• Official Symbol 2: IL6ST
• Synonyms 2: IL6ST; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin-6 receptor subunit beta; CD130; GP130; CD130 antigen; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; membrane glycoprotein gp130; interleukin receptor beta chain; oncostatin-M receptor subunit alpha; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; CDW130; IL-6RB; DKFZp564F053
• Gene ID 2: 3572
• mRNA Refseq 2: NM_001190981
• Protein Refseq 2: NP_001177910
• MIM 2: 600694
• UniProt ID 2: P40189