Recombinant Human OLR1 protein, His-Avi-tagged

• Cat.No.: OLR1-061H
• Product Overview: Human FOLR1 Protein is expressed from mammalian with a poly-His and Avi tag at the C-terminal It contains Arg25-Met233.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: It contains Arg25-Met233 .
• Description: Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The Protein has a calculated MW of 27.5kDa. As a result of glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE.
• Endotoxin: Less than 0.2EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 [ Homo sapiens ]
• Official Symbol: OLR1
• Synonyms: FOLR; FOLR1; FR-alpha;Adult folate-binding protein; FBP; folate binding protein; folate receptor 1 (adult); Folate receptor 1; folate receptor alpha; Folate receptor, adult; Folbp1; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18
• Gene ID: 4973
• mRNA Refseq: NM_001172632
• Protein Refseq: NP_001166103
• MIM: 602601
• UniProt ID: P78380