Recombinant Human NTRK1 protein, Flag-tagged, Biotinylated

• Cat.No.: NTRK1-86H
• Product Overview: Recombinant Human TRKA, cytoplasmic domain [436-790(end) amino acids of accession number NP_001012331.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 44 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Protein length: 436-790 a.a.

Gene Information

• Gene Name: NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
• Official Symbol: NTRK1
• Synonyms: NTRK1; MTC; TRK; TRKA; gp140trk; Oncogene TRK; Trk-A; p140-TrkA; DKFZp781I14186
• Gene ID: 4914
• mRNA Refseq: NM_001007792
• Protein Refseq: NP_001007793
• MIM: 191315
• UniProt ID: P04629
• Chromosome Location: 1q21-q22
• Pathway: ARMS-mediated activation, organism-specific biosystem; Activation of TRKA receptors, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Frs2-mediated activation, organism-specific biosystem
• Function: ATP binding; nerve growth factor binding; NOT nerve growth factor binding; nerve growth factor receptor activity; neurotrophin binding; nucleotide binding; protein binding; protein homodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity