Recombinant Human NRN1 Protein, His-tagged

• Cat.No.: NRN1-777H
• Product Overview: Recombinant Human NRN1(Ala28~Phe142) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 16.2kDa
• Protein length: Ala28~Phe142
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NRN1 neuritin 1 [ Homo sapiens ]
• Official Symbol: NRN1
• Synonyms: NRN1; neuritin 1; neuritin; NRN; dJ380B8.2; MGC44811
• Gene ID: 51299
• mRNA Refseq: NM_016588
• Protein Refseq: NP_057672
• MIM: 607409
• UniProt ID: Q9NPD7