Recombinant Human NRD1 protein, MYC/DDK-tagged

• Cat.No.: NRD1-185H
• Product Overview: Recombinant Human NRD1, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 139.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NRD1 nardilysin (N-arginine dibasic convertase) [ Homo sapiens ]
• Official Symbol: NRD1
• Synonyms: NRD1; nardilysin (N-arginine dibasic convertase); nardilysin; hNRD1; hNRD2; NRD-C; NRD convertase
• Gene ID: 4898
• mRNA Refseq: NM_002525
• Protein Refseq: NP_002516
• MIM: 602651
• UniProt ID: O43847
• Chromosome Location: 1p32.2-p32.1
• Function: epidermal growth factor binding; metal ion binding; metalloendopeptidase activity; peptidase activity; protein binding; zinc ion binding