Recombinant Human NR1H4 Protein, His-tagged

• Cat.No.: NR1H4-16H
• Product Overview: Recombinant Human NR1H4 Protein, His-tagged,expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Phe21-Val297aa
• Description: This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.Purified recombinant protein of Human nuclear receptor subfamily 1, group H, member 4 (NR1H4), transcript variant 2, Phe21-Val297, with N-terminal His tag, expressed in E.coli, 50ug.
• Tag: N-His
• Molecular Mass: 31.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80°C after receiving vials.
• Concentration: >0.05 μg/μL as determined by microplate BCA method
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• GeneID: 9971

Gene Information

• Gene Name: NR1H4 nuclear receptor subfamily 1 group H member 4 [ Homo sapiens (human) ]
• Official Symbol: NR1H4
• Synonyms: BAR,FXR,HRR1,HRR-1,PFIC5,RIP14,NR1H4
• mRNA Refseq: NM_005123
• Protein Refseq: NP_005114
• MIM: 603826
• UniProt ID: Q96RI1