Recombinant Human NPTX2 Protein, DDK-tagged

• Cat.No.: NPTX2-211H
• Product Overview: Recombinant Human NPTX2 fused with DDK tag at C-terminal was expressed in in Sf9 cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Flag
• Description: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
• Molecular Mass: 46.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NPTX2 neuronal pentraxin II [ Homo sapiens (human) ]
• Official Symbol: NPTX2
• Synonyms: NPTX2; NP2; NARP; NP-II; neuronal pentraxin II; neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin
• Gene ID: 4885
• mRNA Refseq: NM_002523
• Protein Refseq: NP_002514
• MIM: 600750
• UniProt ID: P47972