Recombinant Human NOB1 Protein, GST-tagged

Description :	In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]
Source :	Wheat Germ
Species :	Human
Tag :	GST
Molecular Mass :	73.1 kDa
AA Sequence :	MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPETPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR
Applications :	Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array
Notes :	Best use within three months from the date of receipt of this protein.
Storage :	Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer :	50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Name	NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol	NOB1
Synonyms	NOB1; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); PSMD8 binding protein 1 , PSMD8BP1; RNA-binding protein NOB1; ART 4; MST158; nin one binding protein; NOB1P; protein ART-4; PSMD8 binding protein 1; phosphorylation regulatory protein HP-10; adenocarcinoma antigen recognized by T lymphocytes 4; ART-4; MSTP158; PSMD8BP1;
Gene ID	28987
mRNA Refseq	NM_014062
Protein Refseq	NP_054781
MIM	613586
UniProt ID	Q9ULX3