Recombinant Human NNMT, T7 -tagged

• Cat.No.: NNMT-27994TH
• Product Overview: Recombinant full length protein, corresponding to Human NNMT fused with T7 tag at N-terminus.

Specification

• Description: N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
• Conjugation: T7
• Source: E. coli
• Tissue specificity: Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the NNMT/PNMT/TEMT family.
• Full Length: Full L.

Gene Information

• Gene Name: NNMT nicotinamide N-methyltransferase [ Homo sapiens ]
• Official Symbol: NNMT
• Synonyms: NNMT; nicotinamide N-methyltransferase
• Gene ID: 4837
• mRNA Refseq: NM_006169
• Protein Refseq: NP_006160
• MIM: 600008
• Uniprot ID: P40261
• Chromosome Location: 11q23.1
• Pathway: Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem
• Function: methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity