Recombinant Human NMNAT2, His-tagged

• Cat.No.: NMNAT2-638H
• Product Overview: Recombinant Human NMNAT2 is produced inE.coliand fused at the N-terminus to a His-tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Liquid. 0.2µm-filtered solution in 55mM TRIS, pH 8.2, containing 150mM sodium chloride.
• Storage And Stability: -20°C. Stable for at least 3 months after receipt when stored at -20°C. Unstable in solutions containing less than 250mM salt. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: NMNAT2 nicotinamide nucleotide adenylyltransferase 2 [ Homo sapiens ]
• Synonyms: NMNAT2; nicotinamide nucleotide adenylyltransferase 2; PNAT2; C1orf15; MGC2756; KIAA0479; nicotinamide mononucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NaMN adenylyltransferase 2; nicotinate-nucleotide adenylyltransferase 2; pyridine nucleotide adenylyltransferase 2; EC 2.7.7.18; EC 2.7.7.1
• Gene ID: 23057
• mRNA Refseq: NM_015039
• Protein Refseq: NP_055854
• MIM: 608701
• UniProt ID: Q9BZQ4
• Chromosome Location: 1q25
• Pathway: Metabolic pathways; Nicotinate and nicotinamide metabolism; Metabolism of vitamins and cofactors
• Function: ATP binding; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; nucleotide binding; nucleotidyltransferase activity; protein binding; transferase activity