Recombinant Human NFKBID, His-tagged

• Cat.No.: NFKBID-2305H
• Product Overview: Recombinant human NFKBID protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 336aa
• Description: NF-kappa-B inhibitor delta, also known as NFKBID, is a member of the IkB family of proteins can be divided into four groups (IkB-alpha, IkB-beta, IkB-gamma, IkB-epsilon). NFKBID plays a role in the regulation of both inflammatory responses and cytokine, IL-2 and IL-6 expression via NFkB activity. Existing as three alternatively spliced isoforms, NFKBID associates with RelB, NFκB p50 and NFkB p65 in nucleus, and is thought to assist in thymocyte selection in response to TCR induction.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 35.9 kDa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEAGPWR VSAPPSGPPQ FPAVVPGPSL EVARAHMLAL GPQQLLAQDE EGDTLLHLFA ARGLRWAAYAAAEVLQVYRR LDIREHKGKT PLLVAAAANQ PLIVEDLLNL GAEPNAADHQ GRSVLHVAAT YGLPGVLLAV LNSGVQVDLE ARDFEGLTPL HTAILALNVA MRPSDLCPRV LSTQARDRLD CVHMLLQMGA NHTSQEIKSN KTVLHLAVQA ANPTLVQLLL ELPRGDLRTF VNMKAHGNTALHMAAALPPG PAQEAIVRHL LAAGADPTLR NLENEQPVHL LRPGPGPEGL RQLLKRSRVA PPGLSS
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta [ Homo sapiens ]
• Official Symbol: NFKBID
• Synonyms: TA-NFKBH; IkappaBNS; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; 15671; Ensembl:ENSG00000167604; MGC11314, MGC149503; NF-kappa-B inhibitor delta;ikB-delta;ikappaBdelta;I-kappa-B-delta;T-cell activation NFKB-like protein
• Gene ID: 84807
• mRNA Refseq: NM_139239.1
• Protein Refseq: NP_640332.1
• UniProt ID: Q8NI38
• Chromosome Location: 19q13.12
• Function: NF-kappaB binding