Recombinant Human NCKAP1L, GST-tagged

• Cat.No.: NCKAP1L-13732H
• Product Overview: Recombinant Human NCKAP1L protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 453-613a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: NCKAP1L NCK-associated protein 1-like [ Homo sapiens ]
• Official Symbol: NCKAP1L
• Synonyms: NCKAP1L; NCK-associated protein 1-like; HEM1, hematopoietic protein 1; nck-associated protein 1-like; hematopoietic protein 1; membrane-associated protein hem-1; HEM1
• Gene ID: 3071
• mRNA Refseq: NM_001184976
• Protein Refseq: NP_001171905
• MIM: 141180
• UniProt ID: P55160
• Chromosome Location: 12q13.1
• Pathway: Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem
• Function: Rac GTPase activator activity; protein binding; protein complex binding; protein kinase activator activity