Recombinant Human natriuretic peptide C, His-tagged

• Cat.No.: NPPC-251H
• Product Overview: NPPC, 24-126aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 24-126 a.a.
• Description: NPPC is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. Recombinant human NPPC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,
• Molecular Mass: 13.2kDa (126aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKPGAPPK VPRTPPAEEL AEPQAAGGGQ KKGDKAPGGG GANLKGDRSR LLRDLRVDTK SRAAWARLLQ EHPNARKYKG ANKKGLSKGC FGLKLDRIGS MSGLGC
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by BCA assay)

Gene Information

• Gene Name: NPPC natriuretic peptide C [ Homo sapiens ]
• Official Symbol: NPPC
• Synonyms: NPPC; natriuretic peptide C; natriuretic peptide precursor C; C-type natriuretic peptide; CNP; CNP2
• Gene ID: 4880
• mRNA Refseq: NM_024409
• Protein Refseq: NP_077720
• MIM: 600296
• UniProt ID: P23582
• Chromosome Location: 2q24-qter
• Function: hormone activity; peptide hormone receptor binding; protein homodimerization activity; receptor binding