Recombinant Human MUC16 protein, His-tagged

• Cat.No.: MUC16-9382H
• Product Overview: Recombinant Human MUC16(aa 12055-12535) fused with His tag was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 12055-12535 a.a.
• Description: CA-125 is a tumor marker has been shown to be elevated in the blood of some patients with specific types of cancers, or other benign conditions. CA-125 is best known for its role as a biomarker for ovarian but elevated levels have also been associated with endometrial, fallopian tube, lung, breast, and gastrointestinal cancer. CA-125 also known as mucin 16 or MUC16 is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins.
• Form: Liquid. In 1X PBS.
• Molecular Mass: ~75 kDa
• Purity: ≥90% (SDS-PAGE)
• Applications: WB; in vitro Assay
• Storage: Short Term Storage: +4 centigrade;Long Term Storage: -20 centigrade.Avoid freeze/thaw cycles.
• Reconstitution: Soluble in 1X PBS or water

Gene Information

• Gene Name: MUC16 mucin 16, cell surface associated [ Homo sapiens ]
• Official Symbol: MUC16
• Synonyms: MUC16; mucin 16, cell surface associated; mucin-16; CA125; FLJ14303; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125
• Gene ID: 94025
• mRNA Refseq: NM_024690
• Protein Refseq: NP_078966
• MIM: 606154
• UniProt ID: Q8WXI7
• Chromosome Location: 19p13.2
• Pathway: Metabolism of proteins, organism-specific biosystem; O-linked glycosylation of mucins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; Termination of O-glycan biosynthesis, organism-specific biosystem
• Function: protein binding