Recombinant Human MS4A1 protein, His-Avi-tagged

• Cat.No.: MS4A1-420H
• Product Overview: Human CD20 is expressed from E. coli with a his tag and avi tag at the C-terminal. It contains Ile141-Ser188 .

Specification

• Species: Human
• Source: E.coli
• Tag: Avi&His
• Protein Length: It contains Ile141-Ser188.
• Description: B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
• Form: Supplied as 0.22um filtered solution in 20mM PB ,10% glycerol (pH 7.0).
• Molecular Mass: The protein has a predicted MW of 16.8 kDa same as Tris-Bis PAGE.
• Endotoxin: Less than 0.01EU per ug by the LAL method.
• Purity: > 95% as determined by SDS-PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: MS4A1 membrane-spanning 4-domains, subfamily A, member 1 [ Homo sapiens ]
• Official Symbol: MS4A1
• Synonyms: MS4A1;CD20;MS4A-1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 11
• Gene ID: 931
• mRNA Refseq: NM_021950
• Protein Refseq: NP_068769
• MIM: 112210
• UniProt ID: P11836