Recombinant Human MRPS35 Protein, GST/His-tagged

• Cat.No.: MRPS35-1944H
• Product Overview: Recombinant human MRPS35 protein, fused to GST-tagged at N-terminus and His-tagged at C-terminus, was expressed in E. coli

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. [provided by RefSeq, Jul 2010].
• Form: 25 mM Tris, pH 8.0,150 mM NaCl,10% glycerol,1% Sarkosyl.
• Molecular Mass: 62.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MRPS35 mitochondrial ribosomal protein S35 [ Homo sapiens ]
• Official Symbol: MRPS35
• Synonyms: HDCMD11P; MDS023; MRP-S28; MRPS28
• Gene ID: 60488
• mRNA Refseq: NM_021821
• Protein Refseq: NP_068593
• MIM: 611995
• UniProt ID: P82673