Recombinant Human MRPL58 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MRPL58-1896H
• Product Overview: ICT1 MS Standard C13 and N15-labeled recombinant protein (NP_001536) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 23.6 kDa
• AA Sequence: MAATRCLRWGLSRAGVWLLPPPARCPRRALHKQKDGTEFKSIYSLDKLYPESQGSDTAWRVPNGAKQADSDIPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLATAEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDMITEASQTPKEPTKEDVKLHRIRIENMNRERLRQKRIHSAVKTSRRVDMDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MRPL58 mitochondrial ribosomal protein L58 [ Homo sapiens (human) ]
• Official Symbol: MRPL58
• Synonyms: MRPL58; mitochondrial ribosomal protein L58; DS1; DS-1; ICT1; MRP-L58; peptidyl-tRNA hydrolase ICT1, mitochondrial; 39S ribosomal protein L58, mitochondrial; digestion substraction 1; immature colon carcinoma transcript 1 protein; mitochondrial large ribosomal subunit protein ICT1; mitochondrial large ribosomal subunit protein mL62; EC 3.1.1.29
• Gene ID: 3396
• mRNA Refseq: NM_001545
• Protein Refseq: NP_001536
• MIM: 603000
• UniProt ID: Q14197