Recombinant Human/Mouse/Rat/Bovine/Porcine BMP2 Protein

• Cat.No.: BMP2-02H
• Product Overview: Recombinant human/mouse/rat/bovine/porcine BMP-2 protein without tag was expressed in E. coli.
  Animal-free (AOF) and carrier protein-free.
  Mass spectrometry: single species with expected mass.
  Analytical reversed-phase: single sharp peak.
  Recovery from stock vial: >95%

Specification

• Species: Human
• Source: E.coli
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
• Molecular Mass: 26 kDa (dimer)
• Endotoxin: <0.005 EU/μg protein (below level of detection)
• Applications: iPSC and ESC maintenance and Expansion; Chemically defined media
• Storage: Resuspend in 10mM HCl at >100 μg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80 centigrade
• Storage Buffer: Lyophilized from acetonitrile, TFA

Gene Information

• Gene Name: BMP2 bone morphogenetic protein 2 [ Homo sapiens (human) ]
• Official Symbol: BMP2
• Synonyms: BMP2; bone morphogenetic protein 2; BDA2; BMP2A; SSFSC; SSFSC1; bone morphogenetic protein 2; bone morphogenetic protein 2A
• Gene ID: 650
• mRNA Refseq: NM_001200
• Protein Refseq: NP_001191
• MIM: 112261
• UniProt ID: P12643