Recombinant Human MERTK Protein, DDK-tagged

• Cat.No.: MERTK-566H
• Product Overview: Recombinant Human MERTK(Met-Ala21-Ile505) fused with DDK tag at C-terminal was expressed in Sf9 cells.

Specification

• Description: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
• Source: Sf9 cells
• Tag: Flag
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
• Molecular Mass: 52.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Protein length: -21 a.a.

Gene Information

• Gene Name: MERTK c-mer proto-oncogene tyrosine kinase [ Homo sapiens ]
• Official Symbol: MERTK
• Synonyms: MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349
• Gene ID: 10461
• mRNA Refseq: NM_006343
• Protein Refseq: NP_006334
• MIM: 604705
• UniProt ID: Q12866