Recombinant Human MC2R Protein, MYC/DDK-tagged

• Cat.No.: MC2R-700H
• Product Overview: Recombinant human MC2R protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 33.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: melanocortin 2 receptor[ Homo sapiens ]
• Official Symbol: MC2R
• Synonyms: ACTHR; ACTHR
• Gene ID: 4158
• mRNA Refseq: NM_000529.2
• Protein Refseq: NP_000520.1
• MIM: 607397
• UniProt ID: Q01718