Recombinant Human MAPKAPK2

Description :	This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Source :	E. coli
Tissue specificity :	Expressed in all tissues examined.
Form :	Liquid
Purity :	Purified via GST Tag
Storage buffer :	Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities :	Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.Contains 1 protein kinase domain.
Tag :	Non
Full Length :	Full L.

Gene Name	MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 [ Homo sapiens ]
Official Symbol	MAPKAPK2
Synonyms	MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; MAP kinase-activated protein kinase 2;
Gene ID	9261
mRNA Refseq	NM_004759
Protein Refseq	NP_004750
MIM	602006
Uniprot ID	P49137
Chromosome Location	1q32
Pathway	Activated TLR4 signalling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CREB phosphorylation, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem;
Function	ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity;