Recombinant Human MAPK6 Protein (Met1-Met316), His tagged

• Cat.No.: MAPK6-4992H
• Product Overview: Recombinant human MAPK6 (Met1-Met316) fused with His tag was expressed in E. coli.

Specification

• Description: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity) .
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 35.36 kDa
• Protein length: Met1-Met316
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: MAPK6 mitogen-activated protein kinase 6 [ Homo sapiens (human) ]
• Official Symbol: MAPK6
• Synonyms: MAPK6; mitogen-activated protein kinase 6; PRKM6; ERK3; HsT17250; p97MAPK; ERK-3; MAPK 6; p97-MAPK; MAP kinase 6; MAP kinase isoform p97; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; DKFZp686F03189
• Gene ID: 5597
• mRNA Refseq: NM_002748
• Protein Refseq: NP_002739
• MIM: 602904
• UniProt ID: Q16659