Recombinant Human MAGED2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MAGED2-6130H
• Product Overview: MAGED2 MS Standard C13 and N15-labeled recombinant protein (NP_055414) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 65 kDa
• AA Sequence: MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGACGFSYKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MAGED2 MAGE family member D2 [ Homo sapiens (human) ]
• Official Symbol: MAGED2
• Synonyms: MAGED2; melanoma antigen family D, 2; melanoma-associated antigen D2; 11B6; BCG1; breast cancer associated gene 1; HCA10; hepatocellular carcinoma associated protein; hepatocellular carcinoma associated protein HCA10; JCL 1; MAGE D2; MAGED; melanoma associated antigen D2; MGC8386; BCG-1; MAGE-D2 antigen; breast cancer-associated gene 1 protein; hepatocellular carcinoma-associated protein HCA10; hepatocellular carcinoma-associated protein JCL-1; JCL-1; MAGE-D2
• Gene ID: 10916
• mRNA Refseq: NM_014599
• Protein Refseq: NP_055414
• MIM: 300470
• UniProt ID: Q9UNF1