Recombinant Human lymphocyte antigen 86, His-tagged

• Cat.No.: LY86-263H
• Product Overview: LY86, 21-162aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 21-162 a.a.
• Description: LY86 is highly expressed in B-cells, monocytes and tonsil. This protein may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. It is important for efficient CD180 cell surface expression. Recombinant human LY86 protein, fused to His-tag at N-terminus, was expressed in E.coli .
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol, 0.4M Urea
• Molecular Mass: 18.1kDa (165aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSGGGGKAW PTHVVCSDSG LEVLYQSCDP LQDFGFSVEK CSKQLKSNIN IRFGIILRED IKELFLDLAL MSQGSSVLNF SYPICEAALP KFSFCGRRKG EQIYYAGPVN NPEFTIPQGE YQVLLELYTE KRSTVACANA TIMCS
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: LY86 lymphocyte antigen 86 [ Homo sapiens ]
• Official Symbol: LY86
• Synonyms: LY86; lymphocyte antigen 86; dJ80N2.1; MD 1; ly-86; protein MD-1; MD-1, RP105-associated; MD-1; MMD-1; RP1-80N2.1
• Gene ID: 9450
• mRNA Refseq: NM_004271
• Protein Refseq: NP_004262
• MIM: 605241
• UniProt ID: O95711
• Chromosome Location: 6p24.3
• Pathway: Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Toll Like Receptor 4 (TLR4) Cascade, organism-specific biosystem; Toll Receptor Cascades, organism-specific biosystem