Recombinant Human LRSAM1, His-tagged

• Cat.No.: LRSAM1-29433TH
• Product Overview: Recombinant fragment, corresponding to amino acids 491-723 of Human LRSAM1 with N terminal His tag; Predicted MWt 28 kDa.

Specification

• Description: LRSAM1 is a multifunctional RING finger protein that selectively regulates cell adhesion molecules, has ubiquitin ligase activity, and plays a role in receptor endocytosis and viral budding (Li et al.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 149 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: KRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELR EILTELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEE GMERQLVALLEELSAEHYLPIFAHHRLSLDLLSQMSPG DLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMG EVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS S
• Protein length: 491-723 a.a.

Gene Information

• Gene Name: LRSAM1 leucine rich repeat and sterile alpha motif containing 1 [ Homo sapiens ]
• Official Symbol: LRSAM1
• Synonyms: LRSAM1; leucine rich repeat and sterile alpha motif containing 1; E3 ubiquitin-protein ligase LRSAM1; FLJ31641
• Gene ID: 90678
• mRNA Refseq: NM_001190723
• Protein Refseq: NP_001177652
• MIM: 610933
• Uniprot ID: Q6UWE0
• Chromosome Location: 9q34.13
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem
• Function: hormone activity; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity