Recombinant Human LIM2 protein, His & T7-tagged

• Cat.No.: LIM2-7894H
• Product Overview: Recombinant Human LIM2 aa. (Gln30~Phe136 (Accession # P55344)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Gln30~Phe136
• Description: This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.8kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 10.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: LIM2 lens intrinsic membrane protein 2 [ Homo sapiens (human) ]
• Official Symbol: LIM2
• Synonyms: LIM2; lens intrinsic membrane protein 2; MP17; MP19; CTRCT19; lens fiber membrane intrinsic protein; MP18; MP20; lens intrinsic membrane protein 2, 19kDa
• Gene ID: 3982
• mRNA Refseq: NM_001161748.1
• Protein Refseq: NP_001155220.1
• UniProt ID: P55344