Recombinant Human LHB protein, His & T7-tagged

• Cat.No.: LHB-7909H
• Product Overview: Recombinant Human LHB aa. (Glu23~Leu141 (Accession # P01229)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Glu23~Leu141
• Description: This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.8kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.3.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: LHB luteinizing hormone beta polypeptide [ Homo sapiens (human) ]
• Official Symbol: LHB
• Synonyms: LHB; luteinizing hormone beta polypeptide; CGB4; HH23; LSH-B; LSH-beta; lutropin subunit beta; interstitial cell stimulating hormone, beta chain; luteinizing hormone beta subunit; lutropin beta chain
• Gene ID: 3972
• mRNA Refseq: NM_000894.2
• Protein Refseq: NP_000885.1
• UniProt ID: P01229