Recombinant Human LGALS3BP, T7 -tagged

• Cat.No.: LGALS3BP-26801TH
• Product Overview: Recombinant fragment, corresponding to amino acids 19-585 of human LGALS3BP with a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 19-585 a.a.
• Description: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
• Conjugation: T7
• Tissue specificity: Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Contains 1 BACK (BTB/Kelch associated) domain.Contains 1 BTB (POZ) domain.Contains 1 SRCR domain.

Gene Information

• Gene Name: LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein [ Homo sapiens ]
• Official Symbol: LGALS3BP
• Synonyms: LGALS3BP; lectin, galactoside-binding, soluble, 3 binding protein; galectin-3-binding protein; 90K; BTBD17B; L3 antigen; Mac 2 binding protein; MAC 2 BP; serum protein 90K
• Gene ID: 3959
• mRNA Refseq: NM_005567
• Protein Refseq: NP_005558
• MIM: 600626
• Uniprot ID: Q08380
• Chromosome Location: 17q25
• Function: scavenger receptor activity