Recombinant Human LGALS3, MYC/DDK-tagged

• Cat.No.: LGALS3-12H
• Product Overview: Recombinant Human LGALS3, transcript variant 1, fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
• Source: HEK293 cells
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 26 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: LGALS3 lectin, galactoside-binding, soluble, 3 [ Homo sapiens ]
• Official Symbol: LGALS3
• Synonyms: L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2; galectin-3; 35 kDa lectin; IgE-binding protein; MAC-2 antigen; carbohydrate-binding protein 35; galactose-specific lectin 3; laminin-binding protein; lectin L-29
• Gene ID: 3958
• mRNA Refseq: NM_002306
• Protein Refseq: NP_002297
• MIM: 153619
• UniProt ID: P17931
• Chromosome Location: 14q22.3
• Pathway: AGE/RAGE pathway, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: IgE binding; carbohydrate binding; chemoattractant activity